The Butler Institute of American Art says the exhibition opening is the first for Wood at a major American museum.
The 63-year-old British musician plans to be at the museum for a reception on the show's opening day, Sept. 21.
Butler chief curator and director Louis Zona describes Wood's art style as lively and appealing. The museum notes that the rocker picked up a paint brush at the age of 12, before he started playing guitar.
The exhibition includes 30 of Wood's paintings, 22 pen-and-pencil drawings and seven mixed-media works.
The exhibit runs through Nov. 21.